What's your choice of software & why?
Eg. MS Word because I know how to use it, already.
What's your method of production?
Eg. Put all the information together, headings, sub-headings, page headers, page footers.
Put in columns, tables and graphics within the text.
Spend two weeks aligning everything, no orphan table-rows, no orphan paragraphs, etc.

Last put in background images.
Print into PDF with the Office PDF/XPS add-in.